Overview

TriAltus’ TAT-Cre recombinase is a purified, cell-penetrating Cre recombinase protein designed for Cre-lox research workflows where direct protein delivery is preferred. The fusion of Cre recombinase with the TAT peptide enables cellular uptake without the need for genetic transfection, supporting experimental designs that require transient Cre exposure and controlled recombination timing.

Also known as: cell-permeant Cre recombinase, HIV-TAT Cre recombinase, Cre recombinase with NLS, TAT-Cre recombinase fusion protein, recombinant TAT-Cre recombinase

Why Purity and Consistency Matter for TAT-Cre

For protein-based Cre delivery workflows, enzyme purity and batch consistency are critical to experimental reproducibility. Impurities or variable protein composition can influence cellular uptake, background effects, and lot-to-lot consistency in Cre-lox studies. High-purity, well-characterized TAT-Cre supports more predictable handling and experimental control, particularly in workflows that rely on transient recombinase exposure rather than sustained expression.

Bulk Supply & Program Support

TriAltus supports bulk supply and tailored formats for organizations requiring dependable, long-term access to critical enzymes. Production under ISO 13485–compliant processes and the CLīM™ purification platform enable batch consistency and efficient cost-of-goods at scale, supporting volume-based pricing for sustained programs. Contact TriAltus to discuss volume, documentation, packaging, and supply planning.

Key Benefits

• Cell-penetrating TAT-Cre format for direct protein delivery
  

• Tag-free Cre recombinase to minimize unintended interactions
  

• Suitable for transient Cre-lox recombination workflows
  

• Produced for consistency and reproducibility in research use

Specifications

PURITY | ≥95%

ENZYME SOURCE |  TAT-CRE Recombinase is expressed in E. coli with 15 residual amino acids at the C-terminus and is purified with our CLīM technology.

STORAGE/SHIPPING CONCENTRATION | ~ 1 mg/mL

STORAGE BUFFER | 10 mM Tris-Cl pH 8.0, 250 mM NaCl, 50% glycerol

RECOMMENDED STORAGE CONDITIONS | -80°C

EXPIRATION | 6 months from receipt when stored as directed. Avoid repeated freeze/thaw cycles. 

Produced under ISO 13485–compliant processes.

TAT-Cre Recombinase Data Sheet

SKU List

500 µg: 40-2125 | 1 mg: 40-2130 | 5 mg: 40-2135

Applications

Cre-lox Recombination Research

TAT-Cre is commonly used in Cre-lox systems where direct delivery of recombinase protein enables controlled recombination without genetic modification of the target cells.

Transient Recombination Studies

Protein-based delivery allows researchers to study recombination outcomes under defined exposure windows, supporting experimental designs that require temporal control.

Method Development and Optimization

Purified TAT-Cre is suitable for protocol development, including optimization of delivery conditions and recombination timing in cell-based assays.

Learn More

• Learn how TriAltus achieves high purity using CLīM™ purification.

• Explore peer-reviewed publications describing the underlying protein production platform.

• Compare recombinase-based workflows with the Purified CRISPR-Cas9 Protein page.
  

FAQs

Is this Cre recombinase supplied in a protein format?

Yes. TAT-Cre is supplied as a purified recombinase protein for direct delivery workflows.

What is the purpose of the TAT peptide?

The TAT peptide supports cellular uptake of the recombinase protein, enabling protein-based delivery.

Is this product suitable for transient recombination studies?

Yes. Protein-based delivery is commonly used in workflows requiring controlled or transient recombinase exposure.