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Your protein, manufactured.

Your protein, manufactured.

Your protein, manufactured.

U.S.-based contract manufacturing of ultra-pure recombinant enzymes and proteins for diagnostics, life-science tools and biopharma. From a free pilot lot to 100 g+ recurring supply.

U.S.-based contract manufacturing of ultra-pure recombinant enzymes and proteins for diagnostics, life-science tools and biopharma. From a free pilot lot to 100 g+ recurring supply.

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Trusted by industry leaders

Trusted by industry leaders

Trusted by industry leaders

How it works

Prove it on your protein first. Then scale.

1

Pilot

A free pilot lot made to agreed specs, with a full QC data package. You judge it in your own workflow.

2

Scale-up

We lock the process, align QC to your assays, and agree formulation and packaging.

3

Supply

Recurring lots sized to your forecast, with lot-specific CoAs.

Enzyme

Needed

No

Available

Commercially?

Yes

In- House

Expertise?

No

Quality & Cost

Acceptable?

Yes

No

Yes

Make

in-house

Outsource

Compare offerings from commercial suppliers

Spend weeks or months developing products

Trial and error to find reagent that works

Costs savings possible, but opportunity costs of resources committed to non-critical path development

Costs can be prohibitive, even for large companies

About TriAltus Bioscience

Taking the pain
out of outsourcing

At TriAltus, we understand the real-world challenges research teams face when it comes to sourcing high-quality recombinant proteins. Specialty enzymes are essential tools in drug discovery, diagnostics, and synthetic biology — but too often, their cost forces teams to bring production in-house, diverting time, talent, and equipment away from core scientific work.

We believe you shouldn’t have to choose between quality and affordability.

That’s why we built our enzyme platform around CLīM™, a proprietary purification technology that delivers ultra-pure, high-performance proteins in a single purification step. By dramatically lowering the cost of manufacturing, we’re able to pass meaningful savings on to you — making it easier than ever to source the reagents you need without sacrificing quality or scalability.

Whether you're advancing a CRISPR workflow, building a diagnostic assay, or scaling a bioproduction process, TriAltus gives you access to the performance you expect — at a price that lets your team stay focused on what matters most.

Purity, performance, price — you don’t have to compromise.

By the numbers

98%+

Average purity

4x

higher avg titer

33%

lower avg cost

7+

Years of service

200+

Customers

Technology

Powered by CLīM™

Ultra-high affinity

The CL7 tag binds its partner Im7 with near-covalent strength in the femtomolar range.

Ultra-high affinity

The CL7 tag binds its partner Im7 with near-covalent strength in the femtomolar range.

Ultra-high affinity

The CL7 tag binds its partner Im7 with near-covalent strength in the femtomolar range.

Engineered precision

Derived from colicin E7 DNase, CL7 enables unmatched selectivity in protein purification.

Engineered precision

Derived from colicin E7 DNase, CL7 enables unmatched selectivity in protein purification.

Engineered precision

Derived from colicin E7 DNase, CL7 enables unmatched selectivity in protein purification.

Fewer steps, higher yield

Proteins can be purified directly from high-salt lysates with minimal processing.

Fewer steps, higher yield

Proteins can be purified directly from high-salt lysates with minimal processing.

Fewer steps, higher yield

Proteins can be purified directly from high-salt lysates with minimal processing.

Simplified workflow

With CLīM™, expression, binding, washing, and elution happen in a streamlined process.

Simplified workflow

With CLīM™, expression, binding, washing, and elution happen in a streamlined process.

Simplified workflow

With CLīM™, expression, binding, washing, and elution happen in a streamlined process.

Dr. Jennifer Doudna was a co-inventor of CRISPR-Cas 9 gene editing technology, for which she earned the Nobel Prize in Chemistry in 2020. Since 2021, scientists in Doudna’s lab at UC Berkeley have produced more than 100 CRISPR enzymes using TriAltus’ CLīM™ purification system. The same purification technology trusted in CRISPR discovery is behind every TriAltus enzyme.

Recent citations:

Learn more -> about the study in Nature Biotechnology (2024)

Learn more -> about the study in Nucleic Acids Research (2025)

Dr. Jennifer Doudna in Berkeley, Calif., on Jan. 18, 2019.Anastasiia Sapon—The New York Times/Redux

Capabilities and Add on Services

TriAltus Capabilities

Solubility testing

Early solubility checks to ensure protein stability and usability.

FPLC purification

High-resolution purification for precise, reproducible results.

Standard QC quantitation

Reliable quality control with accurate protein quantification.

ISO13485-compliant manufacturing

Strict regulatory compliance for diagnostic-grade proteins.

Custom formulation and packaging

Tailored formulations and packaging designed for downstream applications.

Flexible scale from 10 mg to >100 g

Scalable production to match both research and commercial requirements.

Articles

Insights to keep you informed

Explore our expert insights, guides, and breaking news written to keep you informed & prepared

Tell us about your protein.

Qualifying projects get a free pilot lot through Pilot2Partnership™.