Clean, tag-free protein
in a single
“CL7 is amazing! We were able to purify a protein that we’ve had trouble with in the past.”
—PhD student, University of Chicago
Simplify protein purification with the new CL7 Affinity Tag
The new CL7 Affinity Tag System, exclusively available from TriAltus, is designed to take the hard work and uncertainty out of protein purification. Ideal for scientists with little protein purification experience as well as labs with difficult-to-isolate proteins such as membrane proteins and protein complexes, TriAltus’s CL7 Affinity System does everything you wished a His-tag could do and more.
See why you should be using the CL7 Affinity Tag System
TriAltus Tagging Technology powers research at these organizations
In 2013, crystallographer and UAB Professor Dmitry Vassylyev was purifying proteins for crystallography studies when he began to develop the CL7/Im7 system. At the time, no single affinity chromatography system existed that could give him the desired ultra-high purity, tag-free protein with reasonable yield in a short amount of time.
Biosimilars are functionally significant proteins with therapeutic potential. This blog post highlights the purification of several biosimilar proteins using the CL7/Im7 system.
Membrane proteins are difficult to purify due largely to their hydrophobic regions. When the proteins are in solution, these exposed regions can form strong non-specific interactions with each other, cytoplasmic proteins, or nucleic acids.