Description 

T4 RNA Ligase 2 is an ATP-dependent ligase that catalyzes both inter- and intramolecular ligation of double-stranded RNA, with significantly higher activity on dsRNA nicks than on ssRNA ends; uniquely capable of joining the 3′-hydroxyl of RNA to the 5′-phosphate of DNA within duplex structures, this enzyme is CLīM™-purified for exceptional activity and purity in demanding RNA workflows.
Applications: Double-stranded RNA ligation, RNA-DNA hybrid ligation, Circular RNA construction, RNA repair and splicing studies, Advanced RNA structural probing

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