TriAltus Bioscience: The Story Behind the Name

TriAltus Bioscience – a company whose name is not just a label but a reflection of its mission and achievements in the realm of protein purification. In this article, we explore the meaningful genesis of the TriAltus name and the innovative CLīM technology that it revolves around.

Why is the Company Named 'TriAltus'?

TriAltus Bioscience derives its name from the fusion of two Latin words: "Tri," meaning three, and "Altus," signifying high. This nomenclature is a direct representation of the company's commitment to achieving three vital benchmarks in protein purification: high purity, high yield, and high activity. These standards are not just goals but the foundation upon which TriAltus builds its innovative approaches and solutions in protein science.


What is the Story Behind the Formation of TriAltus Bioscience?

The formation of TriAltus Bioscience centers around the groundbreaking CLīM (CL7/Im7) technology. Developed by researchers at the University of Alabama at Birmingham, including Professor Dmitry Vassylyev, this technology emerged from the need to overcome limitations in existing protein purification methods. The CLīM system, based on the ultra-high-affinity complex between CE7 and Im7, marked a significant advancement in the field, offering a one-step solution that achieves the coveted HHH (high-yield, high-purity, high-activity) purification.


How Does CLīM Technology Set a New Standard in Protein Purification?

CLīM technology is redefining the landscape of protein purification, setting a new benchmark by significantly improving the purification of complex proteins. This tag-based affinity system employs an inactive variant of CE7, named CL7, which maintains full binding affinity to Im7 without any DNA binding or DNase activity. Particularly effective for challenging biological molecules like membrane proteins, multisubunit, and DNA/RNA-binding proteins, CLīM technology excels where other methods face limitations. Unlike traditional affinity methods such as His-Trap, which can bind nonspecifically to other cellular components, the CLīM system ensures specific interaction, reducing background binding and enhancing purity. Its high capacity and stable binding in high-salt buffers, crucial for proteins with intrinsic nucleic acid-binding affinity, outperform other affinity methods in achieving the high yield, high purity, and high activity (HHH) standards. The simplicity, reusability, and broad applicability of the CLīM system make it a superior and invaluable tool in both research and industrial settings, offering a unique advantage in the purification of a diverse range of proteins.


What Makes TriAltus Bioscience Stand Out?

TriAltus Bioscience stands out in the field of biotechnology for its relentless pursuit of innovation, quality, and efficiency. By embracing the CLīM technology, TriAltus has positioned itself at the forefront of protein purification science, offering products and solutions that meet the stringent requirements of today's scientific and industrial challenges. The company's dedication to maintaining the high standards encapsulated in its name is a testament to its commitment to advancing the field of protein science.




To learn more about TriAltus Bioscience and the revolutionary CLīM system, visit Join us as we continue to push the boundaries of protein purification technology.