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AI protein designers

Your designed proteins, made physical.

Your designed proteins, made physical.

Your designed proteins, made physical.

Send us sequences and get purified protein back. Our CLīM affinity purification takes designed variants from sequence to purified protein in a single step, and the same process scales when a winner emerges.

Send us sequences and get purified protein back. Our CLīM affinity purification takes designed variants from sequence to purified protein in a single step, and the same process scales when a winner emerges.

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The problem

Design is fast. The wet lab isn’t.

The expression bottleneck

Models generate designs in hours; producing and purifying them takes your team weeks.

Every variant behaves differently

Custom purification for each design eats time and makes results hard to compare.

A hit, then a scale-up gap

Once a design wins, someone has to make it reliably at milligram-to-gram scale.

What we make

From designed sequence to purified protein.

Designed enzymes and proteins

We express and purify your designs to agreed specs. Your sequences always remain yours.

One purification process

CLīM one-step affinity purification gives you a consistent process across variants.

Scale-up of the winner

The same process carries your lead from pilot quantities to recurring supply.

How it works

Test your designs first. Then scale the winner.

1

Pilot

A free pilot lot of your design made to agreed specs, with a full QC data package.

2

Scale-up

We lock the process for your lead, align QC to your assays and agree formulation.

3

Supply

Recurring lots sized to your program, with lot-specific CoAs.

In practice

50 designed variants, one process

We produced 50 designed protein variants at small scale for an AI protein design team, all through the same CLīM purification process.

Why TriAltus

A manufacturing partner for designed proteins.

CLīM one-step affinity purification

Pilot lots typically in 3–4 weeks

QC by enzymatic activity assays, HPLC-SEC and protein quantitation

Your sequences remain your IP

Have designs ready to test?